S. 854 (119th)Congressional Activities

Risky Research Review Act

Health|Accounting and auditingAdvisory bodies
Sponsor
Cosponsors
Support
Bipartisan
Introduced
Mar 5, 2025
Discussions
Current stageCommittee

Placed on Senate Legislative Calendar under General Orders. Calendar No. 164.

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Bill detailsDiscussionCongressional Activities
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Congressional Activities

Source-heavy congressional process material lives here so the main bill summary can stay focused. Use this tab for committee scheduling, hearings, CRS analysis, committee publications, and amendment text.

CRS reports3
Committee meetings1

CRS Reports

Nonpartisan Congressional Research Service analysis linked directly to this bill.

3 items
Congressional Research Service

CRS analysis

Nonpartisan background and policy analysis tied directly to this bill.

The term gain of function (GOF) refers to any genetic mutation in an organism that confers a new or enhanced ability. Such changes often occur naturally. Additionally, scientists can induce such changes to organisms through experimentation. GOF research covers a broad area of scientific inquiry. One area of GOF resear…

AuthorsTodd Kuiken
Health & Medical R&DGovernment OversightPublic Health Emergency Preparedness & Response
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In the United States, oversight of the life sciences, in particular laboratory biosafety and biosecurity, is exercised pursuant to a mixture of federal law, federal guidance, and self-governance, dependent on the types of experiments and biological agents being used. There currently is no overarching federal law that…

AuthorsTodd Kuiken
Research & Development (R&D) FundingBiosafety & BiosecurityOffice of Science & Technology Policy (OSTP)
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Gain-of-function (GOF) research is a broad area of scientific inquiry that examines how and why an organism gains a new property or an existing property is altered. The terms gain of function and loss of function refer to any genetic mutation in an organism that, respectively, confers a new or enhanced ability or caus…

AuthorsTodd Kuiken
Public Health Emergency Preparedness & ResponseScience for SecurityHealth & Medical R&D
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Committee Meetings

Scheduled or recent committee meetings that mention this bill, plus agenda materials and witness documents.

1 item

Committee meetings

Recent
ScheduledMeetingJul 30, 2025, 2:00 PM
Business meeting to consider S.854, to amend title 31, United States Code, to establish the Life Sciences Research Security Board, S.855, to require executive branch employees to report certain royalties, S.269, to improve coordination between Federal and State agencies and the Do Not Pay working system, S.81, to require a guidance clarity statement on certain agency guidance, S.861, to streamline the sharing of information among Federal disaster assistance agencies, to expedite the delivery of life-saving assistance to disaster survivors, to speed the recovery of communities from disasters, to protect the security and privacy of information provided by disaster survivors, S.766, to require an annual report of taxpayer-funded projects that are over budget and behind schedule, S.872, to amend the Federal Funding Accountability and Transparency Act of 2006 to ensure that other transaction agreements are reported to USAspending.gov, S.727, to correct the inequitable denial of enhanced retirement and annuity benefits to certain U.S. Customs and Border Protection Officers, S.874, to ensure that whistleblowers, including contractors, are protected from retaliation when a Federal employee orders a reprisal, S.594, to amend the Post-Katrina Management Reform Act of 2006 to repeal certain obsolete requirements, S.865, to amend the Lobbying Disclosure Act of 1995 to require certain disclosures by registrants regarding exemptions under the Foreign Agents Registration Act of 1938, as amended, S.856, to amend the Lobbying Disclosure Act of 1995 to clarify a provision relating to certain contents of registrations under that Act, S.850, to amend the Northern Border Security Review Act to require updates to the northern border threat analysis and the northern border strategy, S.848, to provide for joint reports by relevant Federal agencies to Congress regarding incidents of terrorism, and S.572, to enhance the effectiveness of the Shadow Wolves Program; to be immediately followed by a business meeting to consider S.1498, to amend chapter 131 of title 5, United States Code, to prohibit transactions involving certain financial instruments by Members of Congress, the nominations of Pedro Allende, of Florida, to be Under Secretary for Science and Technology, and Sean Plankey, of Pennsylvania, to be Director of the Cybersecurity and Infrastructure Security Agency, both of the Department of Homeland Security, Christopher Fox, of Virginia, to be Inspector General of the Intelligence Community, Office of the Director of National Intelligence, and Edward Aloysius O'Connell, of the District of Columbia, to be an Associate Judge of the Superior Court of the District of Columbia for the term of fifteen years.
342, Dirksen Senate Office Building, 342, Dirksen Senate Office Building
Video
Business meeting to consider S.854, to amend title 31, United States Code, to establish the Life Sciences Research Security Board, S.855, to require executive branch employees to report certain royalties, S.269, to improve coordination between Federal and State agencies and the Do Not Pay working system, S.81, to require a guidance clarity statement on certain agency guidance, S.861, to streamline the sharing of information among Federal disaster assistance agencies, to expedite the delivery of life-saving assistance to disaster survivors, to speed the recovery of communities from disasters, to protect the security and privacy of information provided by disaster survivors, S.766, to require an annual report of taxpayer-funded projects that are over budget and behind schedule, S.872, to amend the Federal Funding Accountability and Transparency Act of 2006 to ensure that other transaction agreements are reported to USAspending.gov, S.727, to correct the inequitable denial of enhanced retirement and annuity benefits to certain U.S. Customs and Border Protection Officers, S.874, to ensure that whistleblowers, including contractors, are protected from retaliation when a Federal employee orders a reprisal, S.594, to amend the Post-Katrina Management Reform Act of 2006 to repeal certain obsolete requirements, S.865, to amend the Lobbying Disclosure Act of 1995 to require certain disclosures by registrants regarding exemptions under the Foreign Agents Registration Act of 1938, as amended, S.856, to amend the Lobbying Disclosure Act of 1995 to clarify a provision relating to certain contents of registrations under that Act, S.850, to amend the Northern Border Security Review Act to require updates to the northern border threat analysis and the northern border strategy, S.848, to provide for joint reports by relevant Federal agencies to Congress regarding incidents of terrorism, and S.572, to enhance the effectiveness of the Shadow Wolves Program; to be immediately followed by a business meeting to consider S.1498, to amend chapter 131 of title 5, United States Code, to prohibit transactions involving certain financial instruments by Members of Congress, the nominations of Pedro Allende, of Florida, to be Under Secretary for Science and Technology, and Sean Plankey, of Pennsylvania, to be Director of the Cybersecurity and Infrastructure Security Agency, both of the Department of Homeland Security, Christopher Fox, of Virginia, to be Inspector General of the Intelligence Community, Office of the Director of National Intelligence, and Edward Aloysius O'Connell, of the District of Columbia, to be an Associate Judge of the Superior Court of the District of Columbia for the term of fifteen years.Business meeting to consider S.854, to amend title 31, United States Code, to establish the Life Sciences Research Security Board, S.855, to require executive branch employees to report certain royalties, S.269, to improve coordination between Federal and State agencies and the Do Not Pay working system, S.81, to require a guidance clarity statement on certain agency guidance, S.861, to streamline the sharing of information among Federal disaster assistance agencies, to expedite the delivery of life-saving assistance to disaster survivors, to speed the recovery of communities from disasters, to protect the security and privacy of information provided by disaster survivors, S.766, to require an annual report of taxpayer-funded projects that are over budget and behind schedule, S.872, to amend the Federal Funding Accountability and Transparency Act of 2006 to ensure that other transaction agreements are reported to USAspending.gov, S.727, to correct the inequitable denial of enhanced retirement and annuity benefits to certain U.S. Customs and Border Protection Officers, S.874, to ensure that whistleblowers, including contractors, are protected from retaliation when a Federal employee orders a reprisal, S.594, to amend the Post-Katrina Management Reform Act of 2006 to repeal certain obsolete requirements, S.865, to amend the Lobbying Disclosure Act of 1995 to require certain disclosures by registrants regarding exemptions under the Foreign Agents Registration Act of 1938, as amended, S.856, to amend the Lobbying Disclosure Act of 1995 to clarify a provision relating to certain contents of registrations under that Act, S.850, to amend the Northern Border Security Review Act to require updates to the northern border threat analysis and the northern border strategy, S.848, to provide for joint reports by relevant Federal agencies to Congress regarding incidents of terrorism, and S.572, to enhance the effectiveness of the Shadow Wolves Program; to be immediately followed by a business meeting to consider S.1498, to amend chapter 131 of title 5, United States Code, to prohibit transactions involving certain financial instruments by Members of Congress, the nominations of Pedro Allende, of Florida, to be Under Secretary for Science and Technology, and Sean Plankey, of Pennsylvania, to be Director of the Cybersecurity and Infrastructure Security Agency, both of the Department of Homeland Security, Christopher Fox, of Virginia, to be Inspector General of the Intelligence Community, Office of the Director of National Intelligence, and Edward Aloysius O'Connell, of the District of Columbia, to be an Associate Judge of the Superior Court of the District of Columbia for the term of fifteen years.

Hearings

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Committee Reports

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Committee Prints

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Amendments

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