The SAFE BOTs Act requires providers of consumer-facing chatbots to disclose clearly and conspicuously to users who are minors that the chatbot is an artificial intelligence system and not a natural person, and to provide crisis hotline resources if a minor raises suicidal ideation. The bill bars chatbots from representing themselves as licensed professionals unless that statement is true, requires providers to implement policies (including advising a break after 3 continuous hours of interaction) addressing sexual material harmful to minors, gambling, and illegal drugs/tobacco/alcohol, and directs a 4-year NIH/NIH-conducted longitudinal study on chatbots and minors' mental health. Enforcement is assigned to the Federal Trade Commission (treating violations as unfair or deceptive acts), gives states parens patriae civil enforcement rights (with notice to and limited coordination with the FTC), preempts state laws on the same covered matters, and takes effect one year after enactment. Definitions include covered user (minor under 17 when the provider has actual knowledge or would know but for willful disregard) and chatbot as an AI system marketed for consumer interactive natural-language communication.