S. 738 (119th)Bill Overview

Dangerous Viral Gain of Function Research Moratorium Act

Health|GeneticsHealth
Cosponsors
Support
Republican
Introduced
Feb 26, 2025
Discussions
Bill Text
Current stageCommittee

Read twice and referred to the Committee on Health, Education, Labor, and Pensions.

Introduced
Committee
Floor
President
Law
Congressional Activities
01 · The brief
Plain-English summaryWhat this bill actually does

The bill prohibits federal research grants to any institution of higher education or research institute that is conducting defined "gain-of-function" research. It defines gain-of-function to include genetic alterations that increase infectivity, transmissibility, pathogenicity, or host range for specified organisms (influenza, coronaviruses, select agents and toxins).

Why people may split

Progressives stress protection of scientific capacity and surveillance.

Watch point

Broad funding ban affecting many universities and agencies; research community opposition likely, though biosecurity supporters exist.

The bill prohibits federal research grants to any institution of higher education or research institute that is conducting defined "gain-of-function" research.

It defines gain-of-function to include genetic alterations that increase infectivity, transmissibility, pathogenicity, or host range for specified organisms (influenza, coronaviruses, select agents and toxins).

The prohibition applies notwithstanding other law and is framed as a moratorium on federally supported dangerous gain-of-function research.

Passage30/100

Contentious subject, broad ban with weak compromise features, strong stakeholder resistance; possible amendments but standalone enactment is uncertain.

CredibilityPartial

How solid the drafting looks.

Contention55/100

Progressives stress protection of scientific capacity and surveillance.

02 · What it does

Who stands to gain, and who may push back.

Likely benefits vs burdens50% / 50%
Federal agenciesFederal agencies

These are examples from the analysis, not a ranked list of the most-affected groups.

Likely helped
  • Federal agenciesReduces federal funding exposure for experiments that elevate pathogen risk, potentially lowering accidental release li…
  • Federal agenciesDecreases national biosecurity risks from federally funded modification of high-consequence organisms.
  • Potential benefitPotentially protects public health, livestock, and agriculture from development of enhanced pathogens.
Likely burdened
  • Potential burdenMay halt or delay fundamental pathogen research needed for vaccines, therapeutics, and countermeasure development.
  • Potential burdenBroad, subjective definitions could produce a chilling effect across many legitimate biological research programs.
  • Federal agenciesCould cause job losses and reduced federal funding at affected universities and research institutes.
03 · Why people split

Why the argument around this bill splits.

Progressives stress protection of scientific capacity and surveillance.
Progressive60%

Cautiously supportive of strong limits on risky pathogen research to protect public health and communities.

Concerned the bill's broad definition and blunt funding ban could hamper essential surveillance, vaccine, and basic science work without clear oversight or mitigation funding.

Split reaction
Centrist50%

Views the moratorium as a reasonable precaution but sees the bill as incomplete.

Wants clearer definitions, targeted scope, sunset or review clauses, and mechanisms to avoid unintended harm to necessary public-health research.

Split reaction
Conservative75%

Generally supportive because it restricts federal funding of high-risk biological experiments and addresses national-security concerns.

Prefers limiting taxpayer support for dangerous research, though some worry about preserving necessary defense-related capabilities.

Leans supportive
04 · Can it pass?

The path through Congress.

Introduced

Reached or meaningfully advanced

Committee

Reached or meaningfully advanced

Floor

Still ahead

President

Still ahead

Law

Still ahead

Passage likelihood30/100

Contentious subject, broad ban with weak compromise features, strong stakeholder resistance; possible amendments but standalone enactment is uncertain.

Scope and complexity
52%
Scopemoderate
52%
Complexitymedium
Why this could stall
  • How agencies would define and monitor 'conducting' gain-of-function research
  • Absence of a formal cost estimate or CBO score in the text
05 · Recent votes

Recent votes on the bill.

No vote history yet

The bill has not accumulated any surfaced votes yet.

06 · Go deeper

Go deeper than the headline read.

Included on this page

Progressives stress protection of scientific capacity and surveillance.

Contentious subject, broad ban with weak compromise features, strong stakeholder resistance; possible amendments but standalone enactment i…

Unlocked analysis

Pro readers get the full perspective split, passage barriers, legislative design review, stakeholder impact map, and lens-based policy tradeoff analysis for Dangerous Viral Gain of Function Research Moratorium Act.

Go beyond the headline summary with full stakeholder mapping, legislative design analysis, passage barriers, and lens-by-lens tradeoff breakdowns.

Perspective breakdownsPassage barriersLegislative design reviewStakeholder impact map
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