S. 1330 (119th)Bill Overview

BRAIN Act

Health|Health
Cosponsors
Support
Bipartisan
Introduced
Apr 8, 2025
Discussions
Bill Text
Current stageCommittee

Read twice and referred to the Committee on Health, Education, Labor, and Pensions.

Introduced
Committee
Floor
President
Law
Congressional Activities
01 · The brief
Plain-English summaryWhat this bill actually does

The BRAIN (Bolstering Research And Innovation Now) Act directs federal actions to advance brain tumor research, improve patient access to clinical trials, and strengthen survivorship care. Key provisions create a public registry for NIH-funded brain tumor biospecimens, authorize new NIH programs and funding for glioblastoma and cellular immunotherapy research, establish a national awareness campaign and demonstration grants for clinical trial and biomarker testing outreach, fund pilot survivorship programs, and require FDA guidance to reduce exclusion of brain tumor patients from trials.

Why people may split

Adequacy of authorized funding versus disease burden and need.

Watch point

Relative to its intended legislative type, this bill is a substantive package that establishes new statutory authorities, reporting obligations, and authorized funding streams to bolster brain tumor research, awareness, and survivorship care.

The BRAIN (Bolstering Research And Innovation Now) Act directs federal actions to advance brain tumor research, improve patient access to clinical trials, and strengthen survivorship care.

Key provisions create a public registry for NIH-funded brain tumor biospecimens, authorize new NIH programs and funding for glioblastoma and cellular immunotherapy research, establish a national awareness campaign and demonstration grants for clinical trial and biomarker testing outreach, fund pilot survivorship programs, and require FDA guidance to reduce exclusion of brain tumor patients from trials.

Passage60/100

Technocratic, bipartisan-appealing package with modest, targeted authorizations; passage depends largely on appropriations and committee prioritization.

CredibilityPartially aligned

Relative to its intended legislative type, this bill is a substantive package that establishes new statutory authorities, reporting obligations, and authorized funding streams to bolster brain tumor research, awareness, and survivorship care. It is generally well-structured in its amendments to the Public Health Service Act and in assigning responsibilities to specific agencies and officials.

Contention30/100

Adequacy of authorized funding versus disease burden and need.

02 · What it does

Who stands to gain, and who may push back.

Likely benefits vs burdens50% / 50%
Federal agencies · WorkersFederal agencies

These are examples from the analysis, not a ranked list of the most-affected groups.

Likely helped
  • Federal agenciesIncreases targeted federal research funding for glioblastoma and cellular immunotherapy development.
  • WorkersA public biospecimen registry can improve researcher access to samples and accelerate collaborations.
  • Potential benefitAwareness campaign may raise clinical trial enrollment and uptake of biomarker testing among patients and clinicians.
Likely burdened
  • Potential burdenNew reporting and registry requirements create administrative burden for hospitals and research institutions.
  • Federal agenciesAuthorized appropriations increase federal spending and create multi-year budgetary commitments.
  • Potential burdenPublic listing of biospecimen collections could raise privacy, proprietary, or consent-related concerns.
03 · Why people split

Why the argument around this bill splits.

Adequacy of authorized funding versus disease burden and need.
Progressive90%

Likely broadly supportive: the bill funds targeted research, increases transparency of biospecimens, promotes access to trials, and directs attention to survivorship and equity-focused outreach.

Supporters would press for larger funding, strong patient protections, and explicit equity measures.

Leans supportive
Centrist80%

Generally supportive in principle: the bill is targeted, bipartisan, and focused on research and patient outreach.

Centrists will seek clear cost estimates, measurable outcomes, and efficient implementation to avoid redundancy and waste.

Leans supportive
Conservative60%

Cautious support for the goal of improving treatments, but concerns about new federal mandates, administrative burdens, and unoffset authorized spending.

Conservatives will emphasize limiting regulatory overreach and protecting privacy and proprietary interests.

Split reaction
04 · Can it pass?

The path through Congress.

Introduced

Reached or meaningfully advanced

Committee

Reached or meaningfully advanced

Floor

Still ahead

President

Still ahead

Law

Still ahead

Passage likelihood60/100

Technocratic, bipartisan-appealing package with modest, targeted authorizations; passage depends largely on appropriations and committee prioritization.

Scope and complexity
52%
Scopemoderate
52%
Complexitymedium
Why this could stall
  • Actual appropriation vs. authorization decisions by Appropriations committees
  • Precise total fiscal cost (some authorizations ambiguous)
05 · Recent votes

Recent votes on the bill.

No vote history yet

The bill has not accumulated any surfaced votes yet.

06 · Go deeper

Go deeper than the headline read.

Included on this page

Adequacy of authorized funding versus disease burden and need.

Technocratic, bipartisan-appealing package with modest, targeted authorizations; passage depends largely on appropriations and committee pr…

Unlocked analysis

Relative to its intended legislative type, this bill is a substantive package that establishes new statutory authorities, reporting obligations, and authorized funding streams to bolster brain tumor research, awareness,…

Go beyond the headline summary with full stakeholder mapping, legislative design analysis, passage barriers, and lens-by-lens tradeoff breakdowns.

Perspective breakdownsPassage barriersLegislative design reviewStakeholder impact map
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